Oral Care - Sealing and Protection of Teeth
Seeking products, technologies or ingredients to provide oral care ingredients for an extended period of time.
Description of the need:
Products, technologies or ingredients that (a) provide a layer, barrier or coating which will inhibit the formation of plaque or biofilm on tooth surfaces and/or (b) provide a coating to protect the teeth from stain and erosive acids or deliver effective amounts of oral care ingredient for an extended period of time.
What we are looking for:
Products, technologies or ingredients that provide protection against attacks, reduce the risk of attacks, and/or improve existing conditions in the oral cavity.
Areas of interest are:
Delivery methods that provide increased contact of oral care actives with teeth and gums, tongue, cheeks, etc.
Continuous and extended oral care treatment
Providing sub-gingival and supra-gingival protection
Enhanced and sustained protection of oral surfaces from caries, hypersensitivity, gingivitis, tartar and plaque related problems
Providing substantive control at night and better morning mouth
Product form could include:
Paste, Gel, Rinse
Strip
Alternate forms/Combination of forms
Devices
Preference is for solutions:
That provide measurable substantivity (remain active in the oral cavity for a prolonged period of time) by
Reducing bacteria in the mouth which increases throughout the night
Neutralizing and/or eliminating bacteria in the mouth, on the teeth and gums
Mitigating plague build-up, tartar build-up and gingivitis
Preventing or protecting oral cavity against plaque re-growth and biofilm formation
Protecting hard tissue surfaces (enamel and dentin) from endogenous and exogenous insults
Where human safety has been confirmed or material(s) are food approved ingredients or GRAS (Generally Recognized As Safe). US monographed ingredients if classified as an OTC in the United States or equivalent from other Board of Health.
That have clinical studies, FDA approval under the appropriate class, or an expedited path to FDA approval or global regulatory opportunities
That are effective at causing clinically significant reductions in plaque and gingivitis
That demonstrate sustained and measurable antimicrobial activity against pathogens involved of gingivitis and periodontitis
Granted or filed patent applications are preferred
We are not interested in:
Solutions that are Rx
Solutions that provide short-term/transitory benefit
Submissions need to have IP or other protection such as Trademark, Copyright or In-market to be considered.
Only non-confidential information can be reviewed.
